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C52

C52Malignant neoplasm of vagina

Billable / specific codeICD-10-CM

C52 is a billable, specific ICD-10-CM code for malignant neoplasm of vagina. It is valid for submission on a claim.

Excludes1 — never code together

These conditions cannot occur together. Billing both on the same encounter is a denial.

  • carcinoma in situ of vagina (D07.2)

Other codes that can never be billed with C52

These codes carry an Excludes1 note pointing at C52. The conflict binds both ways, but ICD-10-CM only writes it down on one side — so you would not find this by reading C52 alone.

  • C44Other and unspecified malignant neoplasm of skin

Risk adjustment

C52 risk-adjusts. Under the CMS-HCC V28 model it maps to this category:

  • HCC 22 Bladder, Colorectal, and Other Cancers0.363 RAF

Coefficient shown for the Community Non-dual Aged segment. A higher HCC in the same hierarchy will suppress this one, so capturing it does not always add score.

Medicare coverage

C52 is named in 56 Medicare coverage policies 56 listing it as supporting medical necessity. Which of them applies to you depends on your Medicare contractor, and coverage genuinely differs by state.

  • A52450Billing and Coding: Paclitaxel (e.g., Taxol®/Abraxane ™)
  • A52480Oral Antiemetic Drugs (Replacement for Intravenous Antiemetics) - Policy Article
  • A54768Billing and Coding: Cardiac Blood Pool Imaging (Multiple Gated Acquisition Scanning- MUGA, Ventriculography) When Performed in Conjunction with Cardiotoxic Chemotherapy
  • A55315Billing and Coding: Proton Beam Therapy

Questions about C52

Is C52 a billable ICD-10-CM code?
Yes. C52 is a billable, specific ICD-10-CM code and is valid for submission on a claim.
Where does C52 sit in the tabular list?
Neoplasms (C00-D49), in the block Malignant neoplasms of female genital organs (C51-C58).
What cannot be coded together with C52?
C52 carries an Excludes1 note, which means the conditions it lists can never be coded together with it on the same encounter.
ICD-10-CMFY2026-Apr· effective April 1, 2026

Loaded directly from the CMS/NCHS ICD-10-CM public-domain release — see data sources and our editorial policy. If this page disagrees with the CMS tabular list, this page is wrong. Reference information for professional coders; not medical or billing advice.