MCMCB Pro
C46.1

C46.1Kaposi's sarcoma of soft tissue

Billable / specific codeICD-10-CM

C46.1 is a billable, specific ICD-10-CM code for kaposi's sarcoma of soft tissue. It is valid for submission on a claim.

Excludes2 — not included here, but may coexist

The excluded condition is not part of this code, but a patient can have both. You may code both.

  • Kaposi's sarcoma of lymph glands and nodes (C46.3)

Inclusion terms

Alternative wordings a physician may use in the chart for this same code.

  • Kaposi's sarcoma of blood vessel
  • Kaposi's sarcoma of connective tissue
  • Kaposi's sarcoma of fascia
  • Kaposi's sarcoma of ligament
  • Kaposi's sarcoma of lymphatic(s) NEC
  • Kaposi's sarcoma of muscle

Other codes that can never be billed with C46.1

These codes carry an Excludes1 note pointing at C46.1. The conflict binds both ways, but ICD-10-CM only writes it down on one side — so you would not find this by reading C46.1 alone.

  • C47Malignant neoplasm of peripheral nerves and autonomic nervous system
  • C48Malignant neoplasm of retroperitoneum and peritoneum

Risk adjustment

C46.1 risk-adjusts. Under the CMS-HCC V28 model it maps to this category:

  • HCC 21 Lymphoma and Other Cancers0.671 RAF

Coefficient shown for the Community Non-dual Aged segment. A higher HCC in the same hierarchy will suppress this one, so capturing it does not always add score.

Medicare coverage

C46.1 is named in 41 Medicare coverage policies 41 listing it as supporting medical necessity. Which of them applies to you depends on your Medicare contractor, and coverage genuinely differs by state.

  • A52370Billing and Coding: Bevacizumab and biosimilars
  • A52450Billing and Coding: Paclitaxel (e.g., Taxol®/Abraxane ™)
  • A52450Billing and Coding: Paclitaxel (e.g., Taxol®/Abraxane ™)
  • A52479Oral Anticancer Drugs - Policy Article

How C46.1 is indexed

Coders do not find codes by browsing the tabular list — they look them up in the alphabetic index, under the word the physician wrote. These are the index entries that lead here, so you can see which chart wordings map to C46.1.

  • Kaposi'ssarcomaconnective tissue
  • SarcomaKaposi'sconnective tissue

Related codes at this level

Codes that share C46. If C46.1 is not quite right, the correct code is usually one of these.

Questions about C46.1

Is C46.1 a billable ICD-10-CM code?
Yes. C46.1 is a billable, specific ICD-10-CM code and is valid for submission on a claim.
Where does C46.1 sit in the tabular list?
Neoplasms (C00-D49), in the block Malignant neoplasms of mesothelial and soft tissue (C45-C49).
ICD-10-CMFY2026-Apr· effective April 1, 2026

Loaded directly from the CMS/NCHS ICD-10-CM public-domain release — see data sources and our editorial policy. If this page disagrees with the CMS tabular list, this page is wrong. Reference information for professional coders; not medical or billing advice.