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C16.0

C16.0Malignant neoplasm of cardia

Billable / specific codeICD-10-CM

C16.0 is a billable, specific ICD-10-CM code for malignant neoplasm of cardia. It is valid for submission on a claim.

Inclusion terms

Alternative wordings a physician may use in the chart for this same code.

  • Malignant neoplasm of cardiac orifice
  • Malignant neoplasm of cardio-esophageal junction
  • Malignant neoplasm of esophagus and stomach
  • Malignant neoplasm of gastro-esophageal junction

Other codes that can never be billed with C16.0

These codes carry an Excludes1 note pointing at C16.0. The conflict binds both ways, but ICD-10-CM only writes it down on one side — so you would not find this by reading C16.0 alone.

  • C15.5Malignant neoplasm of lower third of esophagus

Risk adjustment

C16.0 risk-adjusts. Under the CMS-HCC V28 model it maps to this category:

  • HCC 20 Lung and Other Severe Cancers1.136 RAF

Coefficient shown for the Community Non-dual Aged segment. A higher HCC in the same hierarchy will suppress this one, so capturing it does not always add score.

Medicare coverage

C16.0 is named in 70 Medicare coverage policies 70 listing it as supporting medical necessity. Which of them applies to you depends on your Medicare contractor, and coverage genuinely differs by state.

  • A52450Billing and Coding: Paclitaxel (e.g., Taxol®/Abraxane ™)
  • A52450Billing and Coding: Paclitaxel (e.g., Taxol®/Abraxane ™)
  • A52479Oral Anticancer Drugs - Policy Article
  • A52479Oral Anticancer Drugs - Policy Article

Related codes at this level

Codes that share C16. If C16.0 is not quite right, the correct code is usually one of these.

Questions about C16.0

Is C16.0 a billable ICD-10-CM code?
Yes. C16.0 is a billable, specific ICD-10-CM code and is valid for submission on a claim.
Where does C16.0 sit in the tabular list?
Neoplasms (C00-D49), in the block Malignant neoplasms of digestive organs (C15-C26).
ICD-10-CMFY2026-Apr· effective April 1, 2026

Loaded directly from the CMS/NCHS ICD-10-CM public-domain release — see data sources and our editorial policy. If this page disagrees with the CMS tabular list, this page is wrong. Reference information for professional coders; not medical or billing advice.