MCMedicalCodingSoftware
C00.5

C00.5Malignant neoplasm of lip, unspecified, inner aspect

Billable / specific codeICD-10-CM

C00.5 is a billable, specific ICD-10-CM code for malignant neoplasm of lip, unspecified, inner aspect. It is valid for submission on a claim.

Inclusion terms

Alternative wordings a physician may use in the chart for this same code.

  • Malignant neoplasm of buccal aspect of lip, unspecified
  • Malignant neoplasm of frenulum of lip, unspecified
  • Malignant neoplasm of mucosa of lip, unspecified
  • Malignant neoplasm of oral aspect of lip, unspecified

Excludes1 inherited from the categories above C00.5

These are not written on C00.5, but they bind it: a note on a category applies to every code beneath it. Billing C00.5 with anything listed here is a denial.

Written on C00 Malignant neoplasm of lip

  • malignant melanoma of lip (C43.0)
  • Merkel cell carcinoma of lip (C4A.0)
  • other and unspecified malignant neoplasm of skin of lip (C44.0-)

Other codes that can never be billed with C00.5

These codes carry an Excludes1 note pointing at C00.5. The conflict binds both ways, but ICD-10-CM only writes it down on one side — so you would not find this by reading C00.5 alone.

  • C44.0Other and unspecified malignant neoplasm of skin of lip

Risk adjustment

C00.5 does not map to an HCC and does not risk-adjust under CMS-HCC V28. That is normal — most ICD-10 codes do not. It still needs to be coded correctly; it just will not move a RAF score.

Medicare coverage

C00.5 is named in 57 Medicare coverage policies 57 listing it as supporting medical necessity. Which of them applies to you depends on your Medicare contractor, and coverage genuinely differs by state.

  • A52450Billing and Coding: Paclitaxel (e.g., Taxol®/Abraxane ™)
  • A52479Oral Anticancer Drugs - Policy Article
  • A52479Oral Anticancer Drugs - Policy Article
  • A52479Oral Anticancer Drugs - Policy Article

Code history

C00.5 has not changed since FY2024 — no addition, revision or deletion across the three most recent ICD-10-CM releases.

Related codes at this level

Codes that share C00. If C00.5 is not quite right, the correct code is usually one of these.

Questions about C00.5

Is C00.5 a billable ICD-10-CM code?
Yes. C00.5 is a billable, specific ICD-10-CM code and is valid for submission on a claim.
Where does C00.5 sit in the tabular list?
Neoplasms (C00-D49), in the block Malignant neoplasms of lip, oral cavity and pharynx (C00-C14).
What cannot be coded together with C00.5?
C00.5 carries Excludes1 notes, which means the conditions they list can never be coded together with it on the same encounter. Some are written on the categories above C00.5 (C00) and apply to it just the same.
ICD-10-CMFY2026-Apr· effective April 1, 2026

Loaded directly from the CMS/NCHS ICD-10-CM public-domain release — see data sources and our editorial policy. If this page disagrees with the CMS tabular list, this page is wrong. Reference information for professional coders; not medical or billing advice.