S9988 — Services provided as part of a phase i clinical trial
S9988 is a HCPCS Level II code for services provided as part of a phase i clinical trial. It belongs to the Temporary National Codes (Non-Medicare) section. Medicare does not pay it — see the coverage note below before you bill it.
Medicare coverage: Not payable by Medicare
Medicare does not pay this code. It may still be valid for another payer, but a Medicare claim carrying it will not be reimbursed.
From the coverage field of the CMS Alpha-Numeric HCPCS File, release 2026Q3-Jul. This states Medicare’s position on the code, not on your particular claim.
Physician fee schedule statusI
Not valid for Medicare purposes. Medicare uses another code.
Global period: XXX
Want the dollar amount for your locality? The fee calculator applies your GPCI and the current conversion factor.
The CMS record for S9988
- Long descriptor
- Services provided as part of a phase i clinical trial
- Short descriptor
- Serv part of phase i trial
- Added
- April 1, 2004
- BETOS
- Z2
- Pricing indicator
- 00 — Not priced by Part B
The official wording. This is what the code means.
CMS's 28-character form, which is what shows up on a remittance advice.
When CMS introduced the code.
Berenson-Eggers Type of Service — CMS's own analytic grouping.
Service not separately priced by Part B — not covered, bundled into another service, or used by Part A only.
Codes adjacent to S9988
HCPCS has no hierarchy — related items simply sit next to each other in the numbering. If S9988 is not quite right, the correct code is very often within a few positions of it.
- S9961Ambulance service, conventional air service, nonemergency transport, one way (rotary wing)
- S9970Health club membership, annual
- S9975Transplant related lodging, meals and transportation, per diem
- S9976Lodging, per diem, not otherwise classified
- S9977Meals, per diem, not otherwise specified
- S9981Medical records copying fee, administrative
- S9982Medical records copying fee, per page
- S9986Not medically necessary service (patient is aware that service not medically necessary)
- S9989Services provided outside of the united states of america (list in addition to code(s) for service(s))
- S9990Services provided as part of a phase ii clinical trial
- S9991Services provided as part of a phase iii clinical trial
- S9992Transportation costs to and from trial location and local transportation costs (e.g., fares for taxicab or bus) for clinical trial participant and one caregiver/companion
- S9994Lodging costs (e.g., hotel charges) for clinical trial participant and one caregiver/companion
- S9996Meals for clinical trial participant and one caregiver/companion
- S9999Sales tax
- T1000Private duty / independent nursing service(s) - licensed, up to 15 minutes
Questions about S9988
What is HCPCS code S9988?
S9988 is a HCPCS Level II code for services provided as part of a phase i clinical trial. It sits in the Temporary National Codes (Non-Medicare) section.
Does Medicare cover S9988?
The CMS HCPCS file marks S9988 as "Not payable by Medicare". Medicare does not pay this code. It may still be valid for another payer, but a Medicare claim carrying it will not be reimbursed.
How is S9988 paid under the physician fee schedule?
S9988 carries PFS status code I. Not valid for Medicare purposes. Medicare uses another code.