S8101 — Holding chamber or spacer for use with an inhaler or nebulizer; with mask
S8101 is a HCPCS Level II code for holding chamber or spacer for use with an inhaler or nebulizer; with mask. It belongs to the Temporary National Codes (Non-Medicare) section. Medicare does not pay it — see the coverage note below before you bill it.
Medicare coverage: Not payable by Medicare
Medicare does not pay this code. It may still be valid for another payer, but a Medicare claim carrying it will not be reimbursed.
From the coverage field of the CMS Alpha-Numeric HCPCS File, release 2026Q3-Jul. This states Medicare’s position on the code, not on your particular claim.
Physician fee schedule statusI
Not valid for Medicare purposes. Medicare uses another code.
Global period: XXX
Want the dollar amount for your locality? The fee calculator applies your GPCI and the current conversion factor.
The CMS record for S8101
- Long descriptor
- Holding chamber or spacer for use with an inhaler or nebulizer; with mask
- Short descriptor
- Spacer with mask
- Added
- January 1, 2002
- BETOS
- Z2
- Pricing indicator
- 00 — Not priced by Part B
The official wording. This is what the code means.
CMS's 28-character form, which is what shows up on a remittance advice.
When CMS introduced the code.
Berenson-Eggers Type of Service — CMS's own analytic grouping.
Service not separately priced by Part B — not covered, bundled into another service, or used by Part A only.
Codes adjacent to S8101
HCPCS has no hierarchy — related items simply sit next to each other in the numbering. If S8101 is not quite right, the correct code is very often within a few positions of it.
- S8042Magnetic resonance imaging (mri), low-field
- S8055Ultrasound guidance for multifetal pregnancy reduction(s), technical component (only to be used when the physician doing the reduction procedure does not perform the ultrasound, guidance is included in the cpt code for multifetal pregnancy reduction - 59866)
- S8080Scintimammography (radioimmunoscintigraphy of the breast), unilateral, including supply of radiopharmaceutical
- S8085Fluorine-18 fluorodeoxyglucose (f-18 fdg) imaging using dual-head coincidence detection system (non-dedicated pet scan)
- S8092Electron beam computed tomography (also known as ultrafast ct, cine ct)
- S8096Portable peak flow meter
- S8097Asthma kit (including but not limited to portable peak expiratory flow meter, instructional video, brochure, and/or spacer)
- S8100Holding chamber or spacer for use with an inhaler or nebulizer; without mask
- S8110Peak expiratory flow rate (physician services)
- S8120Oxygen contents, gaseous, 1 unit equals 1 cubic foot
- S8121Oxygen contents, liquid, 1 unit equals 1 pound
- S8130Interferential current stimulator, 2 channel
- S8131Interferential current stimulator, 4 channel
- S8185Flutter device
- S8186Swivel adapter
- S8189Tracheostomy supply, not otherwise classified
Questions about S8101
What is HCPCS code S8101?
S8101 is a HCPCS Level II code for holding chamber or spacer for use with an inhaler or nebulizer; with mask. It sits in the Temporary National Codes (Non-Medicare) section.
Does Medicare cover S8101?
The CMS HCPCS file marks S8101 as "Not payable by Medicare". Medicare does not pay this code. It may still be valid for another payer, but a Medicare claim carrying it will not be reimbursed.
How is S8101 paid under the physician fee schedule?
S8101 carries PFS status code I. Not valid for Medicare purposes. Medicare uses another code.