S4991: Nicotine patches, non-legend
S4991 is a HCPCS Level II code for nicotine patches, non-legend. It belongs to the Temporary National Codes (Non-Medicare) section. Medicare does not pay it: see the coverage note below before you bill it.
Medicare coverage: Not payable by Medicare
Medicare does not pay this code. It may still be valid for another payer, but a Medicare claim carrying it will not be reimbursed.
From the coverage field of the CMS Alpha-Numeric HCPCS File, release 2026Q4-Oct. This states Medicare’s position on the code, not on your particular claim.
Physician fee schedule statusI
Not valid for Medicare purposes. Medicare uses another code.
Global period: XXX
Want the dollar amount for your locality? The fee calculator applies your GPCI and the current conversion factor.
The CMS record for S4991
- Long descriptor
- Nicotine patches, non-legend
- Short descriptor
- Nicotine patch nonlegend
- Added
- January 1, 2002
- BETOS
- Z2
- Pricing indicator
- 00: Not priced by Part B
The official wording. This is what the code means.
CMS's 28-character form, which is what shows up on a remittance advice.
When CMS introduced the code.
Berenson-Eggers Type of Service: CMS's own analytic grouping.
Service not separately priced by Part B, not covered, bundled into another service, or used by Part A only.
Codes adjacent to S4991
HCPCS has no hierarchy: related items simply sit next to each other in the numbering. If S4991 is not quite right, the correct code is very often within a few positions of it.
- S4035Stimulated intrauterine insemination (iui), case rate
- S4037Cryopreserved embryo transfer, case rate
- S4040Monitoring and storage of cryopreserved embryos, per 30 days
- S4042Management of ovulation induction (interpretation of diagnostic tests and studies, non-face-to-face medical management of the patient), per cycle
- S4981Insertion of levonorgestrel-releasing intrauterine system
- S4988Penile contracture device, manual, greater than 3 lbs traction forceterminated
- S4989Contraceptive intrauterine device (e.g., progestacert iud), including implants and supplies
- S4990Nicotine patches, legend
- S4993Contraceptive pills for birth control
- S4995Smoking cessation gum
- S5000Prescription drug, generic
- S5001Prescription drug, brand name
- S50105% dextrose and 0.45% normal saline, 1000 ml
- S50115% dextrose in lactated ringer's, 1000 mlterminated
- S50125% dextrose with potassium chloride, 1000 ml
- S50135% dextrose/0.45% normal saline with potassium chloride and magnesium sulfate, 1000 ml