S4016 — Frozen in vitro fertilization cycle, case rate
S4016 is a HCPCS Level II code for frozen in vitro fertilization cycle, case rate. It belongs to the Temporary National Codes (Non-Medicare) section. Medicare does not pay it — see the coverage note below before you bill it.
Medicare coverage: Not payable by Medicare
Medicare does not pay this code. It may still be valid for another payer, but a Medicare claim carrying it will not be reimbursed.
From the coverage field of the CMS Alpha-Numeric HCPCS File, release 2026Q3-Jul. This states Medicare’s position on the code, not on your particular claim.
Physician fee schedule statusI
Not valid for Medicare purposes. Medicare uses another code.
Global period: XXX
Want the dollar amount for your locality? The fee calculator applies your GPCI and the current conversion factor.
The CMS record for S4016
- Long descriptor
- Frozen in vitro fertilization cycle, case rate
- Short descriptor
- Frozen ivf case rate
- Added
- January 1, 2002
- BETOS
- Z2
- Pricing indicator
- 00 — Not priced by Part B
The official wording. This is what the code means.
CMS's 28-character form, which is what shows up on a remittance advice.
When CMS introduced the code.
Berenson-Eggers Type of Service — CMS's own analytic grouping.
Service not separately priced by Part B — not covered, bundled into another service, or used by Part A only.
Codes adjacent to S4016
HCPCS has no hierarchy — related items simply sit next to each other in the numbering. If S4016 is not quite right, the correct code is very often within a few positions of it.
- S3900Surface electromyography (emg)
- S3902Ballistocardiogram
- S3904Masters two step
- S4005Interim labor facility global (labor occurring but not resulting in delivery)
- S4011In vitro fertilization; including but not limited to identification and incubation of mature oocytes, fertilization with sperm, incubation of embryo(s), and subsequent visualization for determination of development
- S4013Complete cycle, gamete intrafallopian transfer (gift), case rate
- S4014Complete cycle, zygote intrafallopian transfer (zift), case rate
- S4015Complete in vitro fertilization cycle, not otherwise specified, case rate
- S4017Incomplete cycle, treatment cancelled prior to stimulation, case rate
- S4018Frozen embryo transfer procedure cancelled before transfer, case rate
- S4020In vitro fertilization procedure cancelled before aspiration, case rate
- S4021In vitro fertilization procedure cancelled after aspiration, case rate
- S4022Assisted oocyte fertilization, case rate
- S4023Donor egg cycle, incomplete, case rate
- S4024Air polymer-type a intrauterine foam, per study dose
- S4025Donor services for in vitro fertilization (sperm or embryo), case rate
Questions about S4016
What is HCPCS code S4016?
S4016 is a HCPCS Level II code for frozen in vitro fertilization cycle, case rate. It sits in the Temporary National Codes (Non-Medicare) section.
Does Medicare cover S4016?
The CMS HCPCS file marks S4016 as "Not payable by Medicare". Medicare does not pay this code. It may still be valid for another payer, but a Medicare claim carrying it will not be reimbursed.
How is S4016 paid under the physician fee schedule?
S4016 carries PFS status code I. Not valid for Medicare purposes. Medicare uses another code.