S0354 — Treatment planning and care coordination management for cancer, established patient with a change of regimen
S0354 is a HCPCS Level II code for treatment planning and care coordination management for cancer, established patient with a change of regimen. It belongs to the Temporary National Codes (Non-Medicare) section. Medicare does not pay it — see the coverage note below before you bill it.
Medicare coverage: Not payable by Medicare
Medicare does not pay this code. It may still be valid for another payer, but a Medicare claim carrying it will not be reimbursed.
From the coverage field of the CMS Alpha-Numeric HCPCS File, release 2026Q3-Jul. This states Medicare’s position on the code, not on your particular claim.
Physician fee schedule statusI
Not valid for Medicare purposes. Medicare uses another code.
Global period: XXX
Want the dollar amount for your locality? The fee calculator applies your GPCI and the current conversion factor.
The CMS record for S0354
- Long descriptor
- Treatment planning and care coordination management for cancer, established patient with a change of regimen
- Short descriptor
- Cancer treatment plan change
- Added
- April 1, 2012
- BETOS
- Z2
- Pricing indicator
- 00 — Not priced by Part B
The official wording. This is what the code means.
CMS's 28-character form, which is what shows up on a remittance advice.
When CMS introduced the code.
Berenson-Eggers Type of Service — CMS's own analytic grouping.
Service not separately priced by Part B — not covered, bundled into another service, or used by Part A only.
Codes adjacent to S0354
HCPCS has no hierarchy — related items simply sit next to each other in the numbering. If S0354 is not quite right, the correct code is very often within a few positions of it.
- S0315Disease management program; initial assessment and initiation of the program
- S0316Disease management program, follow-up/reassessment
- S0317Disease management program; per diem
- S0320Telephone calls by a registered nurse to a disease management program member for monitoring purposes; per month
- S0340Lifestyle modification program for management of coronary artery disease, including all supportive services; first quarter / stage
- S0341Lifestyle modification program for management of coronary artery disease, including all supportive services; second or third quarter / stage
- S0342Lifestyle modification program for management of coronary artery disease, including all supportive services; fourth quarter / stage
- S0353Treatment planning and care coordination management for cancer, initial treatment
- S0390Routine foot care; removal and/or trimming of corns, calluses and/or nails and preventive maintenance in specific medical conditions (e.g., diabetes), per visit
- S0395Impression casting of a foot performed by a practitioner other than the manufacturer of the orthotic
- S0400Global fee for extracorporeal shock wave lithotripsy treatment of kidney stone(s)
- S0500Disposable contact lens, per lens
- S0504Single vision prescription lens (safety, athletic, or sunglass), per lens
- S0506Bifocal vision prescription lens (safety, athletic, or sunglass), per lens
- S0508Trifocal vision prescription lens (safety, athletic, or sunglass), per lens
- S0510Non-prescription lens (safety, athletic, or sunglass), per lens
Questions about S0354
What is HCPCS code S0354?
S0354 is a HCPCS Level II code for treatment planning and care coordination management for cancer, established patient with a change of regimen. It sits in the Temporary National Codes (Non-Medicare) section.
Does Medicare cover S0354?
The CMS HCPCS file marks S0354 as "Not payable by Medicare". Medicare does not pay this code. It may still be valid for another payer, but a Medicare claim carrying it will not be reimbursed.
How is S0354 paid under the physician fee schedule?
S0354 carries PFS status code I. Not valid for Medicare purposes. Medicare uses another code.