Q4431 — Pma skin substitute product, not otherwise specified (list in addition to primary procedure)
Q4431 is a HCPCS Level II code for pma skin substitute product, not otherwise specified (list in addition to primary procedure). It belongs to the Temporary Codes section. Whether Medicare pays it depends on the coverage rule below.
Medicare coverage: Carrier judgment
Coverage is decided by your Medicare contractor, not by national policy. Whether this is paid depends on the LCD for your jurisdiction and on what the documentation supports.
From the coverage field of the CMS Alpha-Numeric HCPCS File, release 2026Q3-Jul. This states Medicare’s position on the code, not on your particular claim.
Physician fee schedule statusC
Contractor-priced. Your MAC establishes the RVUs and the payment amount case by case, usually after reviewing documentation. There is no national amount to compute.
Global period: XXX
Want the dollar amount for your locality? The fee calculator applies your GPCI and the current conversion factor.
The CMS record for Q4431
- Long descriptor
- Pma skin substitute product, not otherwise specified (list in addition to primary procedure)
- Short descriptor
- Pma skin substitute, nos
- Added
- January 1, 2026
- BETOS
- O1E
- Pricing indicator
- 13 — Physician fee schedule
The official wording. This is what the code means.
CMS's 28-character form, which is what shows up on a remittance advice.
When CMS introduced the code.
Berenson-Eggers Type of Service — CMS's own analytic grouping.
Price established by carriers — not otherwise classified, individual determination, or carrier discretion.
Codes adjacent to Q4431
HCPCS has no hierarchy — related items simply sit next to each other in the numbering. If Q4431 is not quite right, the correct code is very often within a few positions of it.
- Q4422A/c wrap, per square centimeter (add-on, list separately in addition to primary procedure)
- Q4423Biolab tri-membrane wrap flow, per square centimeter (add-on, list separately in addition to primary procedure)
- Q4424Revive ft, per square centimeter (add-on, list separately in addition to primary procedure)
- Q4425Revive tl, per square centimeter (add-on, list separately in addition to primary procedure)
- Q4426Dermabind tl + or dermabind tl x, per square centimeter (add-on, list separately in addition to primary procedure)
- Q4427Dermabind dl n or dermabind dl + or dermabind dl x, per square centimeter (add-on, list separately in addition to primary procedure)
- Q4428Dermabind sl n or dermabind sl + or dermabind sl x, per square centimeter (add-on, list separately in addition to primary procedure)
- Q4429Dermabind ch n or dermabind ch x, per square centimeter (add-on, list separately in addition to primary procedure)
- Q4432510(k) skin substitute product, not otherwise specified (list in addition to primary procedure)
- Q4433361 hct/p skin substitute product, not otherwise specified (list in addition to primary procedure)
- Q4435Renati membrane, per square centimeter (add-on, list separately in addition to primary procedure)
- Q4436Renati ac membrane, per square centimeter (add-on, list separately in addition to primary procedure)
- Q4437Revival ac, per square centimeter (add-on, list separately in addition to primary procedure)
- Q4438Pretect, per square centimeter (add-on, list separately in addition to primary procedure)
- Q4439Instagraft, per square centimeter (add-on, list separately in addition to primary procedure)
- Q4440Curamatrix, per square centimeter (add-on, list separately in addition to primary procedure)
Questions about Q4431
What is HCPCS code Q4431?
Q4431 is a HCPCS Level II code for pma skin substitute product, not otherwise specified (list in addition to primary procedure). It sits in the Temporary Codes section.
Does Medicare cover Q4431?
The CMS HCPCS file marks Q4431 as "Carrier judgment". Coverage is decided by your Medicare contractor, not by national policy. Whether this is paid depends on the LCD for your jurisdiction and on what the documentation supports.
How is Q4431 paid under the physician fee schedule?
Q4431 carries PFS status code C. Contractor-priced. Your MAC establishes the RVUs and the payment amount case by case, usually after reviewing documentation. There is no national amount to compute.