Q4228 — Bionextpatch, per square centimeter
Q4228 is a HCPCS Level II code for bionextpatch, per square centimeter. It belongs to the Temporary Codes section. It was terminated on September 30, 2021 and is not valid on new claims.
This code has been terminated
CMS terminated Q4228 on September 30, 2021. It stays in the file as history — a claim you are auditing from before that date may legitimately carry it — but it must not appear on a new claim. The adjacent codes below are the usual place to look for its replacement.
Medicare coverage: Carrier judgment
Coverage is decided by your Medicare contractor, not by national policy. Whether this is paid depends on the LCD for your jurisdiction and on what the documentation supports.
From the coverage field of the CMS Alpha-Numeric HCPCS File, release 2026Q3-Jul. This states Medicare’s position on the code, not on your particular claim.
The CMS record for Q4228
- Long descriptor
- Bionextpatch, per square centimeter
- Short descriptor
- Bionextpatch, per sq cm
- Added
- July 1, 2020
- Terminated
- September 30, 2021
- BETOS
- O1E
- Pricing indicator
- 51 — Other
The official wording. This is what the code means.
CMS's 28-character form, which is what shows up on a remittance advice.
When CMS introduced the code.
When CMS retired it.
Berenson-Eggers Type of Service — CMS's own analytic grouping.
Drugs.
Codes adjacent to Q4228
HCPCS has no hierarchy — related items simply sit next to each other in the numbering. If Q4228 is not quite right, the correct code is very often within a few positions of it.
- Q4219Surgigraft-dual, per square centimeter (add-on, list separately in addition to primary procedure)
- Q4220Bellacell hd or surederm, per square centimeter (add-on, list separately in addition to primary procedure)
- Q4221Amniowrap2, per square centimeter (add-on, list separately in addition to primary procedure)
- Q4222Progenamatrix, per square centimeter (add-on, list separately in addition to primary procedure)
- Q4224Human health factor 10 amniotic patch (hhf10-p), per square centimeter (add-on, list separately in addition to primary procedure)
- Q4225Amniobind or dermabind tl, per square centimeter (add-on, list separately in addition to primary procedure)
- Q4226Myown skin, includes harvesting and preparation procedures, per square centimeter
- Q4227Amniocore, per square centimeter (add-on, list separately in addition to primary procedure)
- Q4229Cogenex amniotic membrane, per square centimeter (add-on, list separately in addition to primary procedure)
- Q4230Cogenex flowable amnion, per 0.5 cc
- Q4231Corplex p, per ccterminated
- Q4232Corplex, per square centimeter (add-on, list separately in addition to primary procedure)
- Q4233Surfactor or nudyn, per 0.5 cc
- Q4234Xcellerate, per square centimeter (add-on, list separately in addition to primary procedure)
- Q4235Amniorepair or altiply, per square centimeter (add-on, list separately in addition to primary procedure)
- Q4236Carepatch, per square centimeter (add-on, list separately in addition to primary procedure)
Questions about Q4228
What is HCPCS code Q4228?
Q4228 is a HCPCS Level II code for bionextpatch, per square centimeter. It sits in the Temporary Codes section.
Does Medicare cover Q4228?
The CMS HCPCS file marks Q4228 as "Carrier judgment". Coverage is decided by your Medicare contractor, not by national policy. Whether this is paid depends on the LCD for your jurisdiction and on what the documentation supports.
Is Q4228 still valid?
No. Q4228 was terminated on September 30, 2021 and should not be used on new claims.