MCMCB Pro
J9250

J9250Methotrexate sodium, 5 mg

HCPCSTerminatedBETOS O1D

J9250 is a HCPCS Level II code for methotrexate sodium, 5 mg. It belongs to the Drugs Administered Other Than Oral Method section. It was terminated on March 31, 2024 and is not valid on new claims.

This code has been terminated

CMS terminated J9250 on March 31, 2024. It stays in the file as history — a claim you are auditing from before that date may legitimately carry it — but it must not appear on a new claim. The adjacent codes below are the usual place to look for its replacement.

Medicare coverage: Special coverage instructions apply

There are published conditions attached to this code. Check the applicable coverage policy before billing it: the code being valid is not the same as the service being covered.

From the coverage field of the CMS Alpha-Numeric HCPCS File, release 2026Q3-Jul. This states Medicare’s position on the code, not on your particular claim.

The CMS record for J9250

Long descriptor
Methotrexate sodium, 5 mg

The official wording. This is what the code means.

Short descriptor
Methotrexate sodium inj

CMS's 28-character form, which is what shows up on a remittance advice.

Added
January 1, 1994

When CMS introduced the code.

Terminated
March 31, 2024

When CMS retired it.

BETOS
O1D

Berenson-Eggers Type of Service — CMS's own analytic grouping.

Pricing indicator
51 — Other

Drugs.

Codes adjacent to J9250

HCPCS has no hierarchy — related items simply sit next to each other in the numbering. If J9250 is not quite right, the correct code is very often within a few positions of it.

  • J9229Injection, inotuzumab ozogamicin, 0.1 mg
  • J9230Injection, mechlorethamine hydrochloride, (nitrogen mustard), 10 mg
  • J9232Injection, docetaxel (hospira), not therapeutically equivalent to j9171, 1 mg
  • J9245Injection, melphalan hydrochloride, not otherwise specified, 50 mg
  • J9246Injection, melphalan (evomela), 1 mg
  • J9247Injection, melphalan flufenamide, 1mgterminated
  • J9248Injection, melphalan (hepzato), 1 mg
  • J9249Injection, melphalan (apotex), 1 mg
  • J9255Injection, methotrexate (accord), not therapeutically equivalent to j9260, 50 mg
  • J9256Injection, nipocalimab-aahu, 3 mg
  • J9258Injection, paclitaxel protein-bound particles (teva), not therapeutically equivalent to j9264, 1 mgterminated
  • J9259Injection, paclitaxel protein-bound particles (american regent), not therapeutically equivalent to j9264, 1 mgterminated
  • J9260Injection, methotrexate sodium, 50 mg
  • J9261Injection, nelarabine, 50 mg
  • J9262Injection, omacetaxine mepesuccinate, 0.01 mg
  • J9263Injection, oxaliplatin, 0.5 mg

Questions about J9250

What is HCPCS code J9250?

J9250 is a HCPCS Level II code for methotrexate sodium, 5 mg. It sits in the Drugs Administered Other Than Oral Method section.

Does Medicare cover J9250?

The CMS HCPCS file marks J9250 as "Special coverage instructions apply". There are published conditions attached to this code. Check the applicable coverage policy before billing it: the code being valid is not the same as the service being covered.

Is J9250 still valid?

No. J9250 was terminated on March 31, 2024 and should not be used on new claims.

HCPCS Level II2026Q3-Jul· effective July 1, 2026