J9181: Injection, etoposide, 10 mg
J9181 is a HCPCS Level II code for injection, etoposide, 10 mg. It belongs to the Drugs Administered Other Than Oral Method section. It was terminated on September 30, 2026 and is not valid on new claims.
This code has been terminated
CMS terminated J9181 on September 30, 2026. It stays in the file as history: a claim you are auditing from before that date may legitimately carry it, but it must not appear on a new claim. The adjacent codes below are the usual place to look for its replacement.
Medicare coverage: Special coverage instructions apply
There are published conditions attached to this code. Check the applicable coverage policy before billing it: the code being valid is not the same as the service being covered.
From the coverage field of the CMS Alpha-Numeric HCPCS File, release 2026Q4-Oct. This states Medicare’s position on the code, not on your particular claim.
Physician fee schedule statusE
Excluded from the physician fee schedule by regulation. Payment, where it exists, comes from another fee schedule (drugs via ASP, supplies via DMEPOS, and so on).
Global period: XXX
Want the dollar amount for your locality? The fee calculator applies your GPCI and the current conversion factor.
Medically Unlikely Edits: units per day
The most units of J9181 Medicare will pay on one date of service. Bill more on a single line and it is denied. The limit is not the same in every setting, so the row that matters is the one matching the claim you are building.
- practitioner
- 100 units MAI 3: Date of Service Edit: Clinical · Clinical: Society Comment
- outpatient
- 100 units MAI 3: Date of Service Edit: Clinical · Clinical: Society Comment
- DME supplier
- 11 units MAI 3: Date of Service Edit: Clinical · Prescribing Information
The adjudication indicator decides whether exceeding the limit is worth appealing at all: MAI 1 is a line edit you can support with documentation, MAI 3 is a date-of-service edit that is also appealable, and MAI 2 is absolute, no documentation overrides it. CMS MUE 2026Q4.
The CMS record for J9181
- Long descriptor
- Injection, etoposide, 10 mg
- Short descriptor
- Etoposide injection
- Added
- January 1, 1987
- Terminated
- September 30, 2026
- BETOS
- O1D
- Pricing indicator
- 51: Other
The official wording. This is what the code means.
CMS's 28-character form, which is what shows up on a remittance advice.
When CMS introduced the code.
When CMS retired it.
Berenson-Eggers Type of Service: CMS's own analytic grouping.
Drugs.
Codes adjacent to J9181
HCPCS has no hierarchy: related items simply sit next to each other in the numbering. If J9181 is not quite right, the correct code is very often within a few positions of it.
- J9172Injection, docetaxel (docivyx), 1 mg
- J9173Injection, durvalumab, 10 mg
- J9174Injection, docetaxel (beizray), 1 mg
- J9175Injection, elliotts' b solution, 1 ml
- J9176Injection, elotuzumab, 1 mg
- J9177Injection, enfortumab vedotin-ejfv, 0.25 mg
- J9178Injection, epirubicin hcl, 2 mg
- J9179Injection, eribulin mesylate, 0.1 mg
- J9183Gemcitabine intravesical system, 225 mg
- J9184Injection, gemcitabine hydrochloride (avyxa), 200 mg
- J9185Injection, fludarabine phosphate, 50 mg
- J9186Injection, etoposide (avyxa), 1 mg
- J9187Injection, etoposide, 1 mg
- J9190Injection, fluorouracil, 500 mgterminated
- J9191Injection, fluorouracil (avyxa), 10 mg
- J9192Injection, fluorouracil, 10 mg