J3404 — Injection, zopapogene imadenovec-drba suspension, per therapeutic dose
J3404 is a HCPCS Level II code for injection, zopapogene imadenovec-drba suspension, per therapeutic dose. It belongs to the Drugs Administered Other Than Oral Method section. Whether Medicare pays it depends on the coverage rule below.
Medicare coverage: Carrier judgment
Coverage is decided by your Medicare contractor, not by national policy. Whether this is paid depends on the LCD for your jurisdiction and on what the documentation supports.
From the coverage field of the CMS Alpha-Numeric HCPCS File, release 2026Q3-Jul. This states Medicare’s position on the code, not on your particular claim.
Physician fee schedule statusE
Excluded from the physician fee schedule by regulation. Payment, where it exists, comes from another fee schedule (drugs via ASP, supplies via DMEPOS, and so on).
Global period: XXX
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The CMS record for J3404
- Long descriptor
- Injection, zopapogene imadenovec-drba suspension, per therapeutic dose
- Short descriptor
- Inj zopapogene per ther dose
- Added
- April 1, 2026
- BETOS
- O1E
- Pricing indicator
- 51 — Other
The official wording. This is what the code means.
CMS's 28-character form, which is what shows up on a remittance advice.
When CMS introduced the code.
Berenson-Eggers Type of Service — CMS's own analytic grouping.
Drugs.
Codes adjacent to J3404
HCPCS has no hierarchy — related items simply sit next to each other in the numbering. If J3404 is not quite right, the correct code is very often within a few positions of it.
- J3396Injection, verteporfin, 0.1 mg
- J3397Injection, vestronidase alfa-vjbk, 1 mg
- J3398Injection, voretigene neparvovec-rzyl, 1 billion vector genomes
- J3399Injection, onasemnogene abeparvovec-xioi, per treatment, up to 5x10^15 vector genomes
- J3400Injection, triflupromazine hcl, up to 20 mgterminated
- J3401Beremagene geperpavec-svdt for topical administration, containing nominal 5 x 10^9 pfu/ml vector genomes, per 0.1 ml
- J3402Injection, remestemcel-l-rknd, per therapeutic dose
- J3403Revakinagene taroretcel-lwey, per implant
- J3405Injection, onasemnogene abeparvovec-brve, per treatment
- J3410Injection, hydroxyzine hcl, up to 25 mg
- J3411Injection, thiamine hcl, 100 mg
- J3415Injection, pyridoxine hcl, 100 mg
- J3420Injection, vitamin b-12 cyanocobalamin, up to 1000 mcg
- J3424Injection, hydroxocobalamin, intravenous, 25 mg
- J3425Injection, hydroxocobalamin, intramuscular, 10 mcg
- J3430Injection, phytonadione (vitamin k), per 1 mg
Questions about J3404
What is HCPCS code J3404?
J3404 is a HCPCS Level II code for injection, zopapogene imadenovec-drba suspension, per therapeutic dose. It sits in the Drugs Administered Other Than Oral Method section.
Does Medicare cover J3404?
The CMS HCPCS file marks J3404 as "Carrier judgment". Coverage is decided by your Medicare contractor, not by national policy. Whether this is paid depends on the LCD for your jurisdiction and on what the documentation supports.
How is J3404 paid under the physician fee schedule?
J3404 carries PFS status code E. Excluded from the physician fee schedule by regulation. Payment, where it exists, comes from another fee schedule (drugs via ASP, supplies via DMEPOS, and so on).