J3280 — Injection, thiethylperazine maleate, up to 10 mg
J3280 is a HCPCS Level II code for injection, thiethylperazine maleate, up to 10 mg. It belongs to the Drugs Administered Other Than Oral Method section. It was terminated on December 31, 2025 and is not valid on new claims.
This code has been terminated
CMS terminated J3280 on December 31, 2025. It stays in the file as history — a claim you are auditing from before that date may legitimately carry it — but it must not appear on a new claim. The adjacent codes below are the usual place to look for its replacement.
Medicare coverage: Special coverage instructions apply
There are published conditions attached to this code. Check the applicable coverage policy before billing it: the code being valid is not the same as the service being covered.
From the coverage field of the CMS Alpha-Numeric HCPCS File, release 2026Q3-Jul. This states Medicare’s position on the code, not on your particular claim.
The CMS record for J3280
- Long descriptor
- Injection, thiethylperazine maleate, up to 10 mg
- Short descriptor
- Thiethylperazine maleate inj
- Added
- January 1, 1982
- Terminated
- December 31, 2025
- BETOS
- O1E
- Pricing indicator
- 51 — Other
The official wording. This is what the code means.
CMS's 28-character form, which is what shows up on a remittance advice.
When CMS introduced the code.
When CMS retired it.
Berenson-Eggers Type of Service — CMS's own analytic grouping.
Drugs.
Codes adjacent to J3280
HCPCS has no hierarchy — related items simply sit next to each other in the numbering. If J3280 is not quite right, the correct code is very often within a few positions of it.
- J3245Injection, tildrakizumab, 1 mg
- J3246Injection, tirofiban hcl, 0.25 mg
- J3247Injection, secukinumab, intravenous, 1 mg
- J3250Injection, trimethobenzamide hcl, up to 200 mg
- J3260Injection, tobramycin sulfate, up to 80 mg
- J3262Injection, tocilizumab, 1 mg
- J3263Injection, toripalimab-tpzi, 1 mg
- J3265Injection, torsemide, 10 mg/ml
- J3285Injection, treprostinil, 1 mg
- J3290Injection, tranexamic acid, 5 mg
- J3291Injection, tranexamic acid in sodium chloride, 5 mg
- J3299Injection, triamcinolone acetonide (xipere), 1 mg
- J3300Injection, triamcinolone acetonide, preservative free, 1 mg
- J3301Injection, triamcinolone acetonide, not otherwise specified, 10 mg
- J3302Injection, triamcinolone diacetate, per 5 mg
- J3303Injection, triamcinolone hexacetonide, per 5 mg
Questions about J3280
What is HCPCS code J3280?
J3280 is a HCPCS Level II code for injection, thiethylperazine maleate, up to 10 mg. It sits in the Drugs Administered Other Than Oral Method section.
Does Medicare cover J3280?
The CMS HCPCS file marks J3280 as "Special coverage instructions apply". There are published conditions attached to this code. Check the applicable coverage policy before billing it: the code being valid is not the same as the service being covered.
Is J3280 still valid?
No. J3280 was terminated on December 31, 2025 and should not be used on new claims.