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J2315

J2315: Injection, naltrexone, depot form, 1 mg

HCPCSActiveBETOS O1E

J2315 is a HCPCS Level II code for injection, naltrexone, depot form, 1 mg. It belongs to the Drugs Administered Other Than Oral Method section. Whether Medicare pays it depends on the coverage rule below.

Medicare coverage: Carrier judgment

Coverage is decided by your Medicare contractor, not by national policy. Whether this is paid depends on the LCD for your jurisdiction and on what the documentation supports.

From the coverage field of the CMS Alpha-Numeric HCPCS File, release 2026Q4-Oct. This states Medicare’s position on the code, not on your particular claim.

Physician fee schedule statusE

Excluded from the physician fee schedule by regulation. Payment, where it exists, comes from another fee schedule (drugs via ASP, supplies via DMEPOS, and so on).

Global period: XXX

Want the dollar amount for your locality? The fee calculator applies your GPCI and the current conversion factor.

Medically Unlikely Edits: units per day

The most units of J2315 Medicare will pay on one date of service. Bill more on a single line and it is denied. The limit is not the same in every setting, so the row that matters is the one matching the claim you are building.

practitioner
380 units
MAI 3: Date of Service Edit: Clinical · Prescribing Information
outpatient
380 units
MAI 3: Date of Service Edit: Clinical · Prescribing Information
DME supplier
0, never payable
MAI 3: Date of Service Edit: Clinical · CMS Policy

The adjudication indicator decides whether exceeding the limit is worth appealing at all: MAI 1 is a line edit you can support with documentation, MAI 3 is a date-of-service edit that is also appealable, and MAI 2 is absolute, no documentation overrides it. CMS MUE 2026Q4.

The CMS record for J2315

Long descriptor
Injection, naltrexone, depot form, 1 mg

The official wording. This is what the code means.

Short descriptor
Naltrexone, depot form

CMS's 28-character form, which is what shows up on a remittance advice.

Added
January 1, 2007

When CMS introduced the code.

BETOS
O1E

Berenson-Eggers Type of Service: CMS's own analytic grouping.

Pricing indicator
51: Other

Drugs.

Codes adjacent to J2315

HCPCS has no hierarchy: related items simply sit next to each other in the numbering. If J2315 is not quite right, the correct code is very often within a few positions of it.

  • J2290Injection, nafcillin sodium, 20 mg
  • J2291Injection, nafcillin sodium (baxter), 20 mg
  • J2300Injection, nalbuphine hydrochloride, per 10 mg
  • J2305Injection, nitroglycerin, 5 mg
  • J2310Injection, naloxone hydrochloride, per 1 mgterminated
  • J2311Injection, naloxone hydrochloride (zimhi), 1 mgterminated
  • J2312Injection, naloxone hydrochloride, not otherwise specified, 0.01 mg
  • J2313Injection, naloxone hydrochloride (zimhi), 0.01 mg
  • J2320Injection, nandrolone decanoate, up to 50 mg
  • J2323Injection, natalizumab, 1 mg
  • J2325Injection, nesiritide, 0.1 mg
  • J2326Injection, nusinersen, 0.1 mg
  • J2327Injection, risankizumab-rzaa, intravenous, 1 mg
  • J2329Injection, ublituximab-xiiy, 1mg
  • J2350Injection, ocrelizumab, 1 mg
  • J2351Injection, ocrelizumab, 1 mg and hyaluronidase-ocsq
HCPCS Level II2026Q4-Oct· effective October 1, 2026