J1553 — Injection, immune globulin (yimmugo), 100 mg
J1553 is a HCPCS Level II code for injection, immune globulin (yimmugo), 100 mg. It belongs to the Drugs Administered Other Than Oral Method section. Whether Medicare pays it depends on the coverage rule below.
Medicare coverage: Carrier judgment
Coverage is decided by your Medicare contractor, not by national policy. Whether this is paid depends on the LCD for your jurisdiction and on what the documentation supports.
From the coverage field of the CMS Alpha-Numeric HCPCS File, release 2026Q3-Jul. This states Medicare’s position on the code, not on your particular claim.
Physician fee schedule statusE
Excluded from the physician fee schedule by regulation. Payment, where it exists, comes from another fee schedule (drugs via ASP, supplies via DMEPOS, and so on).
Global period: XXX
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The CMS record for J1553
- Long descriptor
- Injection, immune globulin (yimmugo), 100 mg
- Short descriptor
- Inj yimmugo 100 mg
- Added
- April 1, 2026
- BETOS
- O1E
- Pricing indicator
- 51 — Other
The official wording. This is what the code means.
CMS's 28-character form, which is what shows up on a remittance advice.
When CMS introduced the code.
Berenson-Eggers Type of Service — CMS's own analytic grouping.
Drugs.
Codes adjacent to J1553
HCPCS has no hierarchy — related items simply sit next to each other in the numbering. If J1553 is not quite right, the correct code is very often within a few positions of it.
- J1455Injection, foscarnet sodium, per 1000 mg
- J1456Injection, fosaprepitant (teva), not therapeutically equivalent to j1453, 1 mg
- J1457Injection, gallium nitrate, 1 mgterminated
- J1458Injection, galsulfase, 1 mg
- J1459Injection, immune globulin (privigen), intravenous, non-lyophilized (e.g., liquid), 500 mg
- J1460Injection, gamma globulin, intramuscular, 1 cc
- J1551Injection, immune globulin (cutaquig), 100 mg
- J1552Injection, immune globulin (alyglo), 500 mg
- J1554Injection, immune globulin (asceniv), 500 mg
- J1555Injection, immune globulin (cuvitru), 100 mg
- J1556Injection, immune globulin (bivigam), 500 mg
- J1557Injection, immune globulin, (gammaplex), intravenous, non-lyophilized (e.g., liquid), 500 mg
- J1558Injection, immune globulin (xembify), 100 mg
- J1559Injection, immune globulin (hizentra), 100 mg
- J1560Injection, gamma globulin, intramuscular, over 10 cc
- J1561Injection, immune globulin, (gamunex-c/gammaked), non-lyophilized (e.g., liquid), 500 mg
Questions about J1553
What is HCPCS code J1553?
J1553 is a HCPCS Level II code for injection, immune globulin (yimmugo), 100 mg. It sits in the Drugs Administered Other Than Oral Method section.
Does Medicare cover J1553?
The CMS HCPCS file marks J1553 as "Carrier judgment". Coverage is decided by your Medicare contractor, not by national policy. Whether this is paid depends on the LCD for your jurisdiction and on what the documentation supports.
How is J1553 paid under the physician fee schedule?
J1553 carries PFS status code E. Excluded from the physician fee schedule by regulation. Payment, where it exists, comes from another fee schedule (drugs via ASP, supplies via DMEPOS, and so on).