J1453 — Injection, fosaprepitant, 1 mg
J1453 is a HCPCS Level II code for injection, fosaprepitant, 1 mg. It belongs to the Drugs Administered Other Than Oral Method section. Whether Medicare pays it depends on the coverage rule below.
Medicare coverage: Carrier judgment
Coverage is decided by your Medicare contractor, not by national policy. Whether this is paid depends on the LCD for your jurisdiction and on what the documentation supports.
From the coverage field of the CMS Alpha-Numeric HCPCS File, release 2026Q3-Jul. This states Medicare’s position on the code, not on your particular claim.
Physician fee schedule statusE
Excluded from the physician fee schedule by regulation. Payment, where it exists, comes from another fee schedule (drugs via ASP, supplies via DMEPOS, and so on).
Global period: XXX
Want the dollar amount for your locality? The fee calculator applies your GPCI and the current conversion factor.
Medically Unlikely Edits — units per day
The most units of J1453 Medicare will pay on one date of service. Bill more on a single line and it is denied. The limit is not the same in every setting, so the row that matters is the one matching the claim you are building.
- practitioner
- 150 units MAI 3 — Date of Service Edit: Clinical · Prescribing Information
- outpatient
- 150 units MAI 3 — Date of Service Edit: Clinical · Prescribing Information
- DME supplier
- 0 — never payable MAI 3 — Date of Service Edit: Clinical · CMS Policy
The adjudication indicator decides whether exceeding the limit is worth appealing at all: MAI 1 is a line edit you can support with documentation, MAI 3 is a date-of-service edit that is also appealable, and MAI 2 is absolute — no documentation overrides it. CMS MUE 2026Q3.
The CMS record for J1453
- Long descriptor
- Injection, fosaprepitant, 1 mg
- Short descriptor
- Fosaprepitant injection
- Added
- January 1, 2009
- BETOS
- O1E
- Pricing indicator
- 51 — Other
The official wording. This is what the code means.
CMS's 28-character form, which is what shows up on a remittance advice.
When CMS introduced the code.
Berenson-Eggers Type of Service — CMS's own analytic grouping.
Drugs.
Codes adjacent to J1453
HCPCS has no hierarchy — related items simply sit next to each other in the numbering. If J1453 is not quite right, the correct code is very often within a few positions of it.
- J1445Injection, ferric pyrophosphate citrate solution (triferic avnu), 0.1 mg of ironterminated
- J1446Injection, tbo-filgrastim, 5 microgramsterminated
- J1447Injection, tbo-filgrastim, 1 microgram
- J1448Injection, trilaciclib, 1mg
- J1449Injection, eflapegrastim-xnst, 0.1 mg
- J1450Injection fluconazole, 200 mg
- J1451Injection, fomepizole, 15 mg
- J1452Injection, fomivirsen sodium, intraocular, 1.65 mgterminated
- J1454Injection, fosnetupitant 235 mg and palonosetron 0.25 mg
- J1455Injection, foscarnet sodium, per 1000 mg
- J1456Injection, fosaprepitant (teva), not therapeutically equivalent to j1453, 1 mg
- J1457Injection, gallium nitrate, 1 mgterminated
- J1458Injection, galsulfase, 1 mg
- J1459Injection, immune globulin (privigen), intravenous, non-lyophilized (e.g., liquid), 500 mg
- J1460Injection, gamma globulin, intramuscular, 1 cc
- J1551Injection, immune globulin (cutaquig), 100 mg
Questions about J1453
What is HCPCS code J1453?
J1453 is a HCPCS Level II code for injection, fosaprepitant, 1 mg. It sits in the Drugs Administered Other Than Oral Method section.
Does Medicare cover J1453?
The CMS HCPCS file marks J1453 as "Carrier judgment". Coverage is decided by your Medicare contractor, not by national policy. Whether this is paid depends on the LCD for your jurisdiction and on what the documentation supports.
How is J1453 paid under the physician fee schedule?
J1453 carries PFS status code E. Excluded from the physician fee schedule by regulation. Payment, where it exists, comes from another fee schedule (drugs via ASP, supplies via DMEPOS, and so on).