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J0575

J0575Buprenorphine/naloxone, oral, greater than 10 mg buprenorphine

HCPCSActiveBETOS O1E

J0575 is a HCPCS Level II code for buprenorphine/naloxone, oral, greater than 10 mg buprenorphine. It belongs to the Drugs Administered Other Than Oral Method section. Whether Medicare pays it depends on the coverage rule below.

Medicare coverage: Special coverage instructions apply

There are published conditions attached to this code. Check the applicable coverage policy before billing it: the code being valid is not the same as the service being covered.

From the coverage field of the CMS Alpha-Numeric HCPCS File, release 2026Q3-Jul. This states Medicare’s position on the code, not on your particular claim.

Physician fee schedule statusE

Excluded from the physician fee schedule by regulation. Payment, where it exists, comes from another fee schedule (drugs via ASP, supplies via DMEPOS, and so on).

Global period: XXX

Want the dollar amount for your locality? The fee calculator applies your GPCI and the current conversion factor.

Medically Unlikely Edits — units per day

The most units of J0575 Medicare will pay on one date of service. Bill more on a single line and it is denied. The limit is not the same in every setting, so the row that matters is the one matching the claim you are building.

practitioner
0 — never payable
MAI 3 — Date of Service Edit: Clinical · Oral Medication; Not Payable
outpatient
0 — never payable
MAI 3 — Date of Service Edit: Clinical · Oral Medication; Not Payable
DME supplier
0 — never payable
MAI 3 — Date of Service Edit: Clinical · CMS Policy

The adjudication indicator decides whether exceeding the limit is worth appealing at all: MAI 1 is a line edit you can support with documentation, MAI 3 is a date-of-service edit that is also appealable, and MAI 2 is absolute — no documentation overrides it. CMS MUE 2026Q3.

The CMS record for J0575

Long descriptor
Buprenorphine/naloxone, oral, greater than 10 mg buprenorphine

The official wording. This is what the code means.

Short descriptor
Bupren/nal over 10mg bupreno

CMS's 28-character form, which is what shows up on a remittance advice.

Added
January 1, 2015

When CMS introduced the code.

BETOS
O1E

Berenson-Eggers Type of Service — CMS's own analytic grouping.

Pricing indicator
00 — Not priced by Part B

Service not separately priced by Part B — not covered, bundled into another service, or used by Part A only.

Codes adjacent to J0575

HCPCS has no hierarchy — related items simply sit next to each other in the numbering. If J0575 is not quite right, the correct code is very often within a few positions of it.

  • J0561Injection, penicillin g benzathine, 100,000 units
  • J0565Injection, bezlotoxumab, 10 mg
  • J0567Injection, cerliponase alfa, 1 mg
  • J0570Buprenorphine implant, 74.2 mg
  • J0571Buprenorphine, oral, 1 mg
  • J0572Buprenorphine/naloxone, oral, less than or equal to 3 mg buprenorphine
  • J0573Buprenorphine/naloxone, oral, greater than 3 mg, but less than or equal to 6 mg buprenorphine
  • J0574Buprenorphine/naloxone, oral, greater than 6 mg, but less than or equal to 10 mg buprenorphine
  • J0576Injection, buprenorphine extended-release (brixadi), 1 mgterminated
  • J0577Injection, buprenorphine extended-release (brixadi), less than or equal to 7 days of therapy
  • J0578Injection, buprenorphine extended release (brixadi), greater than 7 days and up to 28 days of therapy
  • J0582Injection, bivalirudin (endo), not therapeutically equivalent to j0583, 1 mg
  • J0583Injection, bivalirudin, 1 mg
  • J0584Injection, burosumab-twza 1 mg
  • J0585Injection, onabotulinumtoxina, 1 unit
  • J0586Injection, abobotulinumtoxina, 5 units

Questions about J0575

What is HCPCS code J0575?

J0575 is a HCPCS Level II code for buprenorphine/naloxone, oral, greater than 10 mg buprenorphine. It sits in the Drugs Administered Other Than Oral Method section.

Does Medicare cover J0575?

The CMS HCPCS file marks J0575 as "Special coverage instructions apply". There are published conditions attached to this code. Check the applicable coverage policy before billing it: the code being valid is not the same as the service being covered.

How is J0575 paid under the physician fee schedule?

J0575 carries PFS status code E. Excluded from the physician fee schedule by regulation. Payment, where it exists, comes from another fee schedule (drugs via ASP, supplies via DMEPOS, and so on).

HCPCS Level II2026Q3-Jul· effective July 1, 2026