C9310: Injection, leucovorin calcium (avyxa), 1 mg
C9310 is a HCPCS Level II code for injection, leucovorin calcium (avyxa), 1 mg. It belongs to the Outpatient Prospective Payment System section. It was terminated on September 30, 2026 and is not valid on new claims.
This code has been terminated
CMS terminated C9310 on September 30, 2026. It stays in the file as history: a claim you are auditing from before that date may legitimately carry it, but it must not appear on a new claim. The adjacent codes below are the usual place to look for its replacement.
Medicare coverage: Special coverage instructions apply
There are published conditions attached to this code. Check the applicable coverage policy before billing it: the code being valid is not the same as the service being covered.
From the coverage field of the CMS Alpha-Numeric HCPCS File, release 2026Q4-Oct. This states Medicare’s position on the code, not on your particular claim.
The CMS record for C9310
- Long descriptor
- Injection, leucovorin calcium (avyxa), 1 mg
- Short descriptor
- Inj, leucovorin cal (avyxa)
- Added
- July 1, 2026
- Terminated
- September 30, 2026
- BETOS
- O1E
- Pricing indicator
- 53: Other
The official wording. This is what the code means.
CMS's 28-character form, which is what shows up on a remittance advice.
When CMS introduced the code.
When CMS retired it.
Berenson-Eggers Type of Service: CMS's own analytic grouping.
Statute.
Codes adjacent to C9310
HCPCS has no hierarchy: related items simply sit next to each other in the numbering. If C9310 is not quite right, the correct code is very often within a few positions of it.
- C9302Injection, zanidatamab-hrii, 2 mgterminated
- C9303Injection, zolbetuximab-clzb, 1 mgterminated
- C9304Injection, marstacimab-hncq, 0.5 mgterminated
- C9305Injection, nipocalimab-aahu, 3 mgterminated
- C9306Injection, telisotuzumab vedotin-tllv, 1 mgterminated
- C9307Injection, linvoseltamab-gcpt, 1 mgterminated
- C9308Injection, carboplatin (avyxa), 1 mgterminated
- C9309Injection, onasemnogene abeparvovec-brve, per treatmentterminated
- C9311Injection, eplontersen, 1 mg (code may be used for medicare when drug administered under the direct supervision of a physician, not for use when drug is self administered)
- C9312Injection, trabectedin (apotex), not therapeutically equivalent to j9362, 0.01 mg
- C9313Injection, pivekimab sunirine-pvzy, 0.01 mg
- C9349Puraply, and puraply antimicrobial, any type, per square centimeterterminated
- C9352Microporous collagen implantable tube (neuragen nerve guide), per centimeter length
- C9353Microporous collagen implantable slit tube (neurawrap nerve protector), per centimeter length
- C9354Acellular pericardial tissue matrix of non-human origin (veritas), per square centimeter
- C9355Collagen nerve cuff (neuromatrix), per 0.5 centimeter length