MCMedicalCodingSoftware
C9250

C9250: Human plasma fibrin sealant, vapor-heated, solvent-detergent (artiss), 2 ml

HCPCSActiveBETOS O1E

C9250 is a HCPCS Level II code for human plasma fibrin sealant, vapor-heated, solvent-detergent (artiss), 2 ml. It belongs to the Outpatient Prospective Payment System section. Whether Medicare pays it depends on the coverage rule below.

Medicare coverage: Special coverage instructions apply

There are published conditions attached to this code. Check the applicable coverage policy before billing it: the code being valid is not the same as the service being covered.

From the coverage field of the CMS Alpha-Numeric HCPCS File, release 2026Q4-Oct. This states Medicare’s position on the code, not on your particular claim.

Medically Unlikely Edits: units per day

The most units of C9250 Medicare will pay on one date of service. Bill more on a single line and it is denied. The limit is not the same in every setting, so the row that matters is the one matching the claim you are building.

practitioner
1 unit
MAI 3: Date of Service Edit: Clinical · Clinical: Data
outpatient
5 units
MAI 3: Date of Service Edit: Clinical · Clinical: Data

The adjudication indicator decides whether exceeding the limit is worth appealing at all: MAI 1 is a line edit you can support with documentation, MAI 3 is a date-of-service edit that is also appealable, and MAI 2 is absolute, no documentation overrides it. CMS MUE 2026Q4.

The CMS record for C9250

Long descriptor
Human plasma fibrin sealant, vapor-heated, solvent-detergent (artiss), 2 ml

The official wording. This is what the code means.

Short descriptor
Artiss fibrin sealant

CMS's 28-character form, which is what shows up on a remittance advice.

Added
July 1, 2009

When CMS introduced the code.

BETOS
O1E

Berenson-Eggers Type of Service: CMS's own analytic grouping.

Pricing indicator
53: Other

Statute.

Codes adjacent to C9250

HCPCS has no hierarchy: related items simply sit next to each other in the numbering. If C9250 is not quite right, the correct code is very often within a few positions of it.

  • C9170Injection, tarlatamab-dlle, 1 mgterminated
  • C9171Injection, pegulicianine, 1 mgterminated
  • C9172Injection, fidanacogene elaparvovec-dzkt, per therapeutic doseterminated
  • C9173Injection, filgrastim-txid (nypozi), biosimilar, 1 microgramterminated
  • C9174Injection, datopotamab deruxtecan-dlnk, 1 mgterminated
  • C9175Injection, treosulfan, 50 mgterminated
  • C9176Tc-99m from domestically produced non-heu mo-99, [minimum 50 percent], full cost recovery add-on, per study dose
  • C9248Injection, clevidipine butyrate, 1 mgterminated
  • C9254Injection, lacosamide, 1 mg
  • C9257Injection, bevacizumab, 0.25 mg
  • C9275Injection, hexaminolevulinate hydrochloride, 100 mg, per study doseterminated
  • C9285Lidocaine 70 mg/tetracaine 70 mg, per patch
  • C9290Injection, bupivacaine liposome, 1 mgterminated
  • C9293Injection, glucarpidase, 10 units
  • C9300Injection, indigotindisulfonate sodium, 1 mgterminated
  • C9301Obecabtagene autoleucel, up to 400 million cd19 car-positive viable t cells, including leukapheresis and dose preparation procedures, per therapeutic doseterminated
HCPCS Level II2026Q4-Oct· effective October 1, 2026