C9135 — Factor ix (antihemophilic factor, recombinant), alprolix, per i.u.
C9135 is a HCPCS Level II code for factor ix (antihemophilic factor, recombinant), alprolix, per i.u.. It belongs to the Outpatient Prospective Payment System section. It was terminated on December 31, 2014 and is not valid on new claims.
This code has been terminated
CMS terminated C9135 on December 31, 2014. It stays in the file as history — a claim you are auditing from before that date may legitimately carry it — but it must not appear on a new claim. The adjacent codes below are the usual place to look for its replacement.
Medicare coverage: Special coverage instructions apply
There are published conditions attached to this code. Check the applicable coverage policy before billing it: the code being valid is not the same as the service being covered.
From the coverage field of the CMS Alpha-Numeric HCPCS File, release 2026Q3-Jul. This states Medicare’s position on the code, not on your particular claim.
The CMS record for C9135
- Long descriptor
- Factor ix (antihemophilic factor, recombinant), alprolix, per i.u.
- Short descriptor
- Factor ix (alprolix)
- Added
- October 1, 2014
- Terminated
- December 31, 2014
- BETOS
- O1E
- Pricing indicator
- 53 — Other
The official wording. This is what the code means.
CMS's 28-character form, which is what shows up on a remittance advice.
When CMS introduced the code.
When CMS retired it.
Berenson-Eggers Type of Service — CMS's own analytic grouping.
Statute.
Codes adjacent to C9135
HCPCS has no hierarchy — related items simply sit next to each other in the numbering. If C9135 is not quite right, the correct code is very often within a few positions of it.
- C9098Ciltacabtagene autoleucel, up to 100 million autologous b-cell maturation antigen (bcma) directed car-positive t cells, including leukapheresis and dose preparation procedures, per therapeutic doseterminated
- C9101Injection, oliceridine, 0.1 mg
- C9113Injection, pantoprazole sodium, per vialterminated
- C9121Injection, argatroban, per 5 mgterminated
- C9122Mometasone furoate sinus implant, 10 micrograms (sinuva)terminated
- C9132Prothrombin complex concentrate (human), kcentra, per i.u. of factor ix activityterminated
- C9133Factor ix (antihemophilic factor, recombinant), rixubis, per i.u.terminated
- C9134Factor xiii (antihemophilic factor, recombinant), tretten, per 10 i.u.terminated
- C9136Injection, factor viii, fc fusion protein, (recombinant), per i.u.terminated
- C9137Injection, factor viii (antihemophilic factor, recombinant) pegylated, 1 i.u.terminated
- C9138Injection, factor viii (antihemophilic factor, recombinant) (nuwiq), 1 i.u.terminated
- C9139Injection, factor ix, albumin fusion protein (recombinant), idelvion, 1 i.u.terminated
- C9140Injection, factor viii (antihemophilic factor, recombinant) (afstyla), 1 i.u.terminated
- C9141Injection, factor viii, (antihemophilic factor, recombinant), pegylated-aucl (jivi), 1 i.u.terminated
- C9142Injection, bevacizumab-maly, biosimilar, (alymsys), 10 mgterminated
- C9143Cocaine hydrochloride nasal solution (numbrino), 1 mg
Questions about C9135
What is HCPCS code C9135?
C9135 is a HCPCS Level II code for factor ix (antihemophilic factor, recombinant), alprolix, per i.u.. It sits in the Outpatient Prospective Payment System section.
Does Medicare cover C9135?
The CMS HCPCS file marks C9135 as "Special coverage instructions apply". There are published conditions attached to this code. Check the applicable coverage policy before billing it: the code being valid is not the same as the service being covered.
Is C9135 still valid?
No. C9135 was terminated on December 31, 2014 and should not be used on new claims.