C9091 — Injection, sirolimus protein-bound particles, 1 mg
C9091 is a HCPCS Level II code for injection, sirolimus protein-bound particles, 1 mg. It belongs to the Outpatient Prospective Payment System section. It was terminated on June 30, 2022 and is not valid on new claims.
This code has been terminated
CMS terminated C9091 on June 30, 2022. It stays in the file as history — a claim you are auditing from before that date may legitimately carry it — but it must not appear on a new claim. The adjacent codes below are the usual place to look for its replacement.
Medicare coverage: Special coverage instructions apply
There are published conditions attached to this code. Check the applicable coverage policy before billing it: the code being valid is not the same as the service being covered.
From the coverage field of the CMS Alpha-Numeric HCPCS File, release 2026Q3-Jul. This states Medicare’s position on the code, not on your particular claim.
The CMS record for C9091
- Long descriptor
- Injection, sirolimus protein-bound particles, 1 mg
- Short descriptor
- Sirolimus, protein-bound,1mg
- Added
- April 1, 2022
- Terminated
- June 30, 2022
- BETOS
- O1D
- Pricing indicator
- 53 — Other
The official wording. This is what the code means.
CMS's 28-character form, which is what shows up on a remittance advice.
When CMS introduced the code.
When CMS retired it.
Berenson-Eggers Type of Service — CMS's own analytic grouping.
Statute.
Codes adjacent to C9091
HCPCS has no hierarchy — related items simply sit next to each other in the numbering. If C9091 is not quite right, the correct code is very often within a few positions of it.
- C9083Injection, amivantamab-vmjw, 10 mgterminated
- C9084Injection, loncastuximab tesirine-lpyl, 0.1 mgterminated
- C9085Injection, avalglucosidase alfa-ngpt, 4 mgterminated
- C9086Injection, anifrolumab-fnia, 1 mgterminated
- C9087Injection, cyclophosphamide, (auromedics), 10 mgterminated
- C9088Instillation, bupivacaine and meloxicam, 1 mg/0.03 mgterminated
- C9089Bupivacaine, collagen-matrix implant, 1 mgterminated
- C9090Injection, plasminogen, human-tvmh, 1 mgterminated
- C9092Injection, triamcinolone acetonide, suprachoroidal (xipere), 1 mgterminated
- C9093Injection, ranibizumab, via sustained release intravitreal implant (susvimo), 0.1 mgterminated
- C9094Inj, sutimlimab-jome, 10 mgterminated
- C9095Inj, tebentafusp-tebn, 1 mcgterminated
- C9096Injection, filgrastim-ayow, biosimilar, (releuko), 1 microgramterminated
- C9097Inj, faricimab-svoa, 0.1 mgterminated
- C9098Ciltacabtagene autoleucel, up to 100 million autologous b-cell maturation antigen (bcma) directed car-positive t cells, including leukapheresis and dose preparation procedures, per therapeutic doseterminated
- C9101Injection, oliceridine, 0.1 mg
Questions about C9091
What is HCPCS code C9091?
C9091 is a HCPCS Level II code for injection, sirolimus protein-bound particles, 1 mg. It sits in the Outpatient Prospective Payment System section.
Does Medicare cover C9091?
The CMS HCPCS file marks C9091 as "Special coverage instructions apply". There are published conditions attached to this code. Check the applicable coverage policy before billing it: the code being valid is not the same as the service being covered.
Is C9091 still valid?
No. C9091 was terminated on June 30, 2022 and should not be used on new claims.