A4100 — Non-sheet form skin substitute, fda cleared as a device, not otherwise specified (list in addition to primary procedure)
A4100 is a HCPCS Level II code for non-sheet form skin substitute, fda cleared as a device, not otherwise specified (list in addition to primary procedure). It belongs to the Transportation, Medical & Surgical Supplies, Administrative section. Whether Medicare pays it depends on the coverage rule below.
Medicare coverage: Carrier judgment
Coverage is decided by your Medicare contractor, not by national policy. Whether this is paid depends on the LCD for your jurisdiction and on what the documentation supports.
From the coverage field of the CMS Alpha-Numeric HCPCS File, release 2026Q3-Jul. This states Medicare’s position on the code, not on your particular claim.
Physician fee schedule statusC
Contractor-priced. Your MAC establishes the RVUs and the payment amount case by case, usually after reviewing documentation. There is no national amount to compute.
Global period: XXX
Want the dollar amount for your locality? The fee calculator applies your GPCI and the current conversion factor.
The CMS record for A4100
- Long descriptor
- Non-sheet form skin substitute, fda cleared as a device, not otherwise specified (list in addition to primary procedure)
- Short descriptor
- Nosht skin sub fda clrd nos
- Added
- April 1, 2022
- BETOS
- P5A
- Pricing indicator
- 13 — Physician fee schedule
The official wording. This is what the code means.
CMS's 28-character form, which is what shows up on a remittance advice.
When CMS introduced the code.
Berenson-Eggers Type of Service — CMS's own analytic grouping.
Price established by carriers — not otherwise classified, individual determination, or carrier discretion.
Codes adjacent to A4100
HCPCS has no hierarchy — related items simply sit next to each other in the numbering. If A4100 is not quite right, the correct code is very often within a few positions of it.
- A2038Marigen pacto, per square centimeter (add-on, list separately in addition to primary procedure)
- A2039Innovamatrix fd, per square centimeter (add-on, list separately in addition to primary procedure)
- A2040Microlyte painguard, per square centimeter
- A2041Foundation drs+ duo, per square centimeter
- A2042Foundation drs+ solo, per square centimeter
- A2043Biobrane, per square centimeter
- A2044Biobrane glove, each
- A2045Novashield or novogen wound matrix, per square centimeter
- A4206Syringe with needle, sterile, 1 cc or less, each
- A4207Syringe with needle, sterile 2 cc, each
- A4208Syringe with needle, sterile 3 cc, each
- A4209Syringe with needle, sterile 5 cc or greater, each
- A4210Needle-free injection device, each
- A4211Supplies for self-administered injections
- A4212Non-coring needle or stylet with or without catheter
- A4213Syringe, sterile, 20 cc or greater, each
Questions about A4100
What is HCPCS code A4100?
A4100 is a HCPCS Level II code for non-sheet form skin substitute, fda cleared as a device, not otherwise specified (list in addition to primary procedure). It sits in the Transportation, Medical & Surgical Supplies, Administrative section.
Does Medicare cover A4100?
The CMS HCPCS file marks A4100 as "Carrier judgment". Coverage is decided by your Medicare contractor, not by national policy. Whether this is paid depends on the LCD for your jurisdiction and on what the documentation supports.
How is A4100 paid under the physician fee schedule?
A4100 carries PFS status code C. Contractor-priced. Your MAC establishes the RVUs and the payment amount case by case, usually after reviewing documentation. There is no national amount to compute.