E34.321 — Primary insulin-like growth factor-1 (IGF-1) deficiency
E34.321 is a billable, specific ICD-10-CM code for primary insulin-like growth factor-1 (igf-1) deficiency. It is valid for submission on a claim.
Inclusion terms
Alternative wordings a physician may use in the chart for this same code.
- Acid-labile subunit gene (IGFALS) defect
- Growth hormone gene 1 (GH1) defect with growth hormone neutralizing antibodies
- Growth hormone insensitivity syndrome (GHIS)
- Insulin-like growth factor 1 gene (IGF1) defect
- Laron type short stature
- Severe primary insulin-like growth factor-1 deficiency (SPIGFD)
- Signal transducer and activator of transcription 5B gene (STAT5b) defect
Risk adjustment
E34.321 does not map to an HCC and does not risk-adjust under CMS-HCC V28. That is normal — most ICD-10 codes do not. It still needs to be coded correctly; it just will not move a RAF score.
Medicare coverage
E34.321 is named in 1 Medicare coverage policy — 1 listing it as supporting medical necessity. Which of them applies to you depends on your Medicare contractor, and coverage genuinely differs by state.
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How E34.321 is indexed
Coders do not find codes by browsing the tabular list — they look them up in the alphabetic index, under the word the physician wrote. These are the index entries that lead here, so you can see which chart wordings map to E34.321.
- Dwarfism›Laron-type
- Short, shortening, shortness›stature NEC›Laron-type
- Short, shortening, shortness›stature NEC›due to›genetic causes›acid-labile subunit gene defect(IGFALS)
- Short, shortening, shortness›stature NEC›due to›genetic causes›growth hormone gene 1 defect with growth hormone neutralizing antibodies(GH1)
- Short, shortening, shortness›stature NEC›due to›genetic causes›growth hormone insensitivity syndrome(GHIS)
- Short, shortening, shortness›stature NEC›due to›genetic causes›insulin-like growth factor 1 gene defect(IGF1)
- Short, shortening, shortness›stature NEC›due to›genetic causes›primary insulin-like growth factor-1 deficiency(IGF-1)
- Short, shortening, shortness›stature NEC›due to›genetic causes›severe primary insulin-like growth factor-1 deficiency(SPIGFD)
- Short, shortening, shortness›stature NEC›due to›genetic causes›signal transducer and activator of transcription 5B gene defect(STAT5b)
Related codes at this level
Codes that share E34.32. If E34.321 is not quite right, the correct code is usually one of these.
Questions about E34.321
- Is E34.321 a billable ICD-10-CM code?
- Yes. E34.321 is a billable, specific ICD-10-CM code and is valid for submission on a claim.
- Where does E34.321 sit in the tabular list?
- Endocrine, nutritional and metabolic diseases (E00-E89), in the block Disorders of other endocrine glands (E20-E35).